Checkpoint Inhibitors Side Effects

The most common side effects of checkpoint inhibitors are.

Checkpoint inhibitors side effects.

After about six months of therapy john tells you that over the past four weeks he has been experiencing increased fatigue weight gain insomnia and constipation. Other immune checkpoint inhibitors are under clinical evaluation. Common side effects associated with currently approved checkpoint immunotherapies may include but are not limited to. Besides headache dizziness and apathy ataxia tremor paralysis myoclonus cognitive impairment speech disorders and even seizures may occur.

Diarrhea pneumonitis inflammation in the lungs rashes and itchiness problems with some hormone levels kidney infections. Paying careful attention to potential symptoms is therefore crucial. Fatigue rash colitis infusion related reactions diarrhea asthenia arthralgias constipation decreased appetite cough dyspnea headache insomnia nausea pain including in the abdomen back and musculoskeletal system peripheral edema pneumonitis radiation pneumonitis pruritus pyrexia vomiting and weight loss. He says he figures these are just normal side effects of his medication.

Occasional any grade toxicities in 5 20 of patients include fatigue headache arthralgia rash pruritus pneumonitis diarrhoea and or colitis hepatitis and endocrinopathies table 1. Mp inflammatory reactions involving the skin and the gastrointestinal tract are among the most common adverse events seen with checkpoint inhibitors. Fatigue weakness nausea confusion headache loss of appetite vision problems fever. On average symptoms appear around nine weeks after starting treatment and may include.

Checkpoint inhibitor associated neurological side effects are rare but potentially life threatening.